Immunization of rats with synthetic peptide constructs from the glucan-binding or catalytic region of mutans streptococcal glucosyltransferase protects against dental caries.

Title:

Immunization of rats with synthetic peptide constructs from the glucan-binding or catalytic region of mutans streptococcal glucosyltransferase protects against dental caries.

Dataset

identifier:	1485267
description:	epitope description:TGAQTIKGQKLYFKANGQQVKG antigen name:KxYKxGKxW signal domain protein host organism:Rattus norvegicus CD Charles River
aggregation:	instance of dataset
availability:	available
primaryPublications:	7622235

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1009117
landingPage:	http://www.iedb.org/assay/1485267

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	1995

Dimension

study type:	b cell assays
subject species:	Streptococcus downei

Person

fullName:	M A Taubman C J Holmberg D J Smith

Data Type

method:	ELISA

Study

name:	Immunization of rats with synthetic peptide constructs from the glucan-binding or catalytic region of mutans streptococcal glucosyltransferase protects against dental caries.
description:	Serum IgG and salivary IgA from epitope-immunized rats recognized the epitope by ELISA. Infection with either Streptococcus sobrinus or Streptococcus mutans of the immunized rats increased the titer of epitope-specific antibodies.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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