Identification of amino acids critical for IgE-binding to sequential epitopes of bovine kappa-casein and the similarity of these epitopes to the corresponding human kappa-casein sequence.

Title:

Identification of amino acids critical for IgE-binding to sequential epitopes of bovine kappa-casein and the similarity of these epitopes to the corresponding human kappa-casein sequence.

Dataset

identifier:	1486826
description:	epitope description:AKYIPIQYVLSRYP antigen name:Bos d 12 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	18186809

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012280
landingPage:	http://www.iedb.org/assay/1486826

Publication

type:	Literature
publicationVenue:	Allergy
dates:	2008

Dimension

study type:	b cell assays
subject species:	Bos taurus

Person

fullName:	N Han K M Jä rvinen R R Cocco P J Busse H A Sampson K Beyer

Data Type

method:	western blot

Study

name:	Identification of amino acids critical for IgE-binding to sequential epitopes of bovine kappa-casein and the similarity of these epitopes to the corresponding human kappa-casein sequence.
description:	Using alanine substitution, the critical amino acids, Q7 and L10, were determined

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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