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Title: T-helper and humoral responses to Puumala hantavirus nucleocapsid protein: identification of T-helper epitopes in a mouse model.
identifier: 1487309
description:
epitope description:DIQEEITRHE
antigen name:Puumala orthohantavirus protein
host organism:Mus musculus BALB/c
antibody name:Mouse sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 11125166
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/836
landingPage: http://www.iedb.org/assay/1487309
type:
Literature
publicationVenue:
J Gen Virol
dates:
2001
study type: b cell assays
subject species: Puumala virus Kazan
fullName:
C de Carvalho Nicacio
M Sä
llberg
C Hultgren
A Lundkvist
method:
ELISA
name:
T-helper and humoral responses to Puumala hantavirus nucleocapsid protein: identification of T-helper epitopes in a mouse model.
description:
Sera from rN protein-primed H-2d mice were restimulated with 86 overlapping 10-mer peptides spanning the whole PUUV N protein. The highest reactivity was seen against residues within the first 120 amino acids, showing that the major antigenic region of the protein is located within the N-terminus. Reactivity was similar in CBA and C57BL/6 mice.

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