Potentiation of immune response against the RESA peptides of Plasmodium falciparum by incorporating a universal T-cell epitope (CS.T3) and an immunomodulator (polytuftsin), and delivery through liposomes.

Title:

Dataset

identifier:	1487414
description:	epitope description:EENVEHDAEENVEHDA antigen name:DNAJ protein, putative host organism:Mus musculus FVB/J antibody name:Mouse sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	10480553

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012243
landingPage:	http://www.iedb.org/assay/1487414

Publication

type:	Literature
publicationVenue:	Microbiol Immunol
dates:	1999

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	P Kumar S Biswas D N Rao

Data Type

method:	ELISA

Study

name:	Potentiation of immune response against the RESA peptides of Plasmodium falciparum by incorporating a universal T-cell epitope (CS.T3) and an immunomodulator (polytuftsin), and delivery through liposomes.
description:	Sera from FVB/J mice immunized with the epitope conjugated to CS.T3 containing polytuftsin entrapped in liposomes showed the highest binding affinity, with KD values 2-4-fold lower than the other vaccine formulations. In a separate assay, antibody sub-typing revealed predominantly IgG2b and IgG2a isotypes.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.