Neutralization sites of type O1 foot-and-mouth disease virus defined by monoclonal antibodies and neutralization-escape virus variants.

Title:

Neutralization sites of type O1 foot-and-mouth disease virus defined by monoclonal antibodies and neutralization-escape virus variants.

identifier:	1487437
description:	epitope description:L868, L872 antigen name:Polyprotein host organism:Mus musculus BALB/c antibody name:13DD2.1.1
aggregation:	instance of dataset
availability:	available
primaryPublications:	2827379

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain O1) (O1 Brugge)

fullName:	J W Stave J L Card D O Morgan V N Vakharia

method:	biological activity

name:	Neutralization sites of type O1 foot-and-mouth disease virus defined by monoclonal antibodies and neutralization-escape virus variants.
description:	MAb 13DD2.1.1, which binds the epitopic residues, cross-neutralized FMDV O1 strains Kaufbeuren and BFS, which share the epitopic residues. MAb 13DD2.1.1 did not neutralize FMDV O1 strain Campos, which has a Leu144Val alteration, or O1 strain Caseros, or FMDV types A12 or C3 Resende.

name:	iedb
homePage:	http://www.iedb.org

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