Use of monoclonal antibodies to identify four neutralization immunogens on a common cold picornavirus, human rhinovirus 14.

Title:

Use of monoclonal antibodies to identify four neutralization immunogens on a common cold picornavirus, human rhinovirus 14.

identifier:	1487671
description:	epitope description:N403, R406, E409, G534, K854 antigen name:Genome polyprotein host organism:Mus musculus antibody name:21, 22, 24, 33, 25, 31
aggregation:	instance of dataset
availability:	available
primaryPublications:	2416951

study type:	b cell assays
subject species:	Rhinovirus B14

fullName:	B Sherry A G Mosser R J Colonno R R Rueckert

method:	biological activity

name:	Use of monoclonal antibodies to identify four neutralization immunogens on a common cold picornavirus, human rhinovirus 14.
description:	The sequence is from the reference cited: Stanway et al.(1984) Nuc Acids Res 12: 7859-7875 [PMID: 6093056]. The epitopic residues in the NIm-III antigenic site recognized by the mAbs was determined by sequencing variant viruses selected with the mAbs. Variants with mutation N72I, R75G, R75K, R75M, E78K, E78V, or G203D in VP3 or K287I in VP1 were not neutralized by the mAbs.

name:	iedb
homePage:	http://www.iedb.org

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