Identification of immunodominant neutralizing epitopes on the hemagglutinin protein of rinderpest virus.

Title:

Identification of immunodominant neutralizing epitopes on the hemagglutinin protein of rinderpest virus.

identifier:	1488142
description:	epitope description:DSGTRK antigen name:Hemagglutinin glycoprotein host organism:Mus musculus antibody name:mAb 59
aggregation:	instance of dataset
availability:	available
primaryPublications:	11799164

study type:	b cell assays
subject species:	Rinderpest virus (strain L)

fullName:	Makoto Sugiyama Naoto Ito Nobuyuki Minamoto Seiichi Tanaka

method:	biological activity

name:	Identification of immunodominant neutralizing epitopes on the hemagglutinin protein of rinderpest virus.
description:	Mab-resistant escape mutants were selected against a wild-type L stain of RPV. The mAb was able to bind to wt virus but not to virus with mutations in the epitopic region. The epitope defines the critical residues and may be conformational.

name:	iedb
homePage:	http://www.iedb.org

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