Subgroup specific protection of mice from respiratory syncytial virus infection with peptides encompassing the amino acid region 174-187 from the G glycoprotein: the role of cysteinyl residues in protection.

Title:

Dataset

identifier:	1488617
description:	epitope description:VPCSICSNNPTCWAICK antigen name:Major surface glycoprotein G host organism:Mus musculus BALB/c
aggregation:	instance of dataset
availability:	available
primaryPublications:	9141214

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006500
landingPage:	http://www.iedb.org/assay/1488617

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1997

Dimension

study type:	b cell assays
subject species:	Human respiratory syncytial virus A strain Long

Person

fullName:	C Simard F Nadon C Sé guin N N Thien H Binz J Basso J F Laliberté M

Data Type

method:	in vivo assay

Study

name:	Subgroup specific protection of mice from respiratory syncytial virus infection with peptides encompassing the amino acid region 174-187 from the G glycoprotein: the role of cysteinyl residues in protection.
description:	This epitope is conserved in strain Long of RSV subgroup A and in strain 8/60 of RSV subgroup B. Epitope immunization protected mice from infection with either strain Long of RSV subgroup A or strain 8/80 of RSV subgroup B. Combinations of cysteine residues C173, C176, C182, and C186 greatly influenced protective activities.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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