Anti-hepatitis A virus antibody response elicited in mice by different forms of a synthetic VP1 peptide.

Title:

Anti-hepatitis A virus antibody response elicited in mice by different forms of a synthetic VP1 peptide.

identifier:	1488643
description:	epitope description:TVSTEQNVPDPQVGI antigen name:Genome polyprotein host organism:Mus musculus antibody name:anti-VP1 peptide
aggregation:	instance of dataset
availability:	available
primaryPublications:	8569533

study type:	b cell assays
subject species:	Hepatovirus A

fullName:	I Haro R M Pinto J F Gonzalez-Dankaart J A Perez F Reig A Bosch

method:	ELISA

name:	Anti-hepatitis A virus antibody response elicited in mice by different forms of a synthetic VP1 peptide.
description:	The KLH-coupled epitope was the most immunogenic and produced a response in 50% of immunized mice at a dose of 2.3 µg. Liposome-entrapped epitope or a MAP form of the epitope produced a response in 3 of 6 mice at higher doses of 50 or 100 µg, respectively. Free peptide produced a response in 1 of 4 mice at a dose of 100 µg. The response to KLH-coupled epitope or liposome-entrapped epitope appeared earlier and was more sustained than the other immunogen forms.

name:	iedb
homePage:	http://www.iedb.org

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