Single-amino-acid mutation in the HA alters the recognition of H9N2 influenza virus by a monoclonal antibody.

Title:

Single-amino-acid mutation in the HA alters the recognition of H9N2 influenza virus by a monoclonal antibody.

identifier:	1488755
description:	epitope description:S145 antigen name:Hemagglutinin host organism:Mus musculus BALB/c antibody name:C/B3
aggregation:	instance of dataset
availability:	available
primaryPublications:	18424263

study type:	b cell assays
subject species:	Influenza A virus (A/chicken/Shandong/6/96(H9N2))

fullName:	Jihui Ping Chengjun Li Guohua Deng Yongping Jiang Guobin Tian Shuxia Zhang Zhigao Bu Hualan Chen

method:	biological activity

name:	Single-amino-acid mutation in the HA alters the recognition of H9N2 influenza virus by a monoclonal antibody.
description:	The residue S145 was determined to be a key residue for the binding of the mAb C/B3 by hemagglutination inhibition, neutralization and immunofluorescence assays of wild type (CK/SD/96) and variant (CK/GX/99) viruses as well as reassortment chimera of these viruses.

name:	iedb
homePage:	http://www.iedb.org

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