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identifier: 1488909
description:
epitope description:LNEEAERWVRQNPPGPN
antigen name:gag protein
host organism:Capra hircus
antibody name:Goat sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 10475088
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1011483
landingPage: http://www.iedb.org/assay/1488909
type:
Literature
publicationVenue:
Virus Res
dates:
1999
study type: b cell assays
subject species: Visna/maedi virus
fullName:
S Rosati
A Mannelli
N Ponti
method:
ELISA
name:
Characterization of the immunodominant cross-reacting epitope of visna maedi virus and caprine arthritis-encephalitis virus capsid antigen.
description:
Four different recombinant subunits of ovine lentivirus p25 were tested against sera from infected goats. The highest ELISA absorbances were obtained with a 29 amino acid subunit located in the N-terminal half of p25. Through the analysis of overlapping peptides spanning this region the authors identified a 17 amino acid sequence as being shared by all fragments. This peptide is therefore considered a potential immunodominant and cross-reactive epitope. The conserved domain between CAEV and MMV is LNEEA + RW-R-NPP---.

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