Location of amino acid residues important for the structure and biological function of the haemagglutinin-neuraminidase glycoprotein of Sendai virus by analysis of escape mutants.

Title:

Location of amino acid residues important for the structure and biological function of the haemagglutinin-neuraminidase glycoprotein of Sendai virus by analysis of escape mutants.

Dataset

identifier:	1492077
description:	epitope description:R279, K461 antigen name:Hemagglutinin-neuraminidase host organism:Mus musculus BALB/c antibody name:63, 50
aggregation:	instance of dataset
availability:	available
primaryPublications:	1849969

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1010416
landingPage:	http://www.iedb.org/assay/1492077

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	1991

Dimension

study type:	b cell assays
subject species:	Sendai virus (strain Enders)

Person

fullName:	D Lyn M B Mazanec J G Nedrud A Portner

Data Type

method:	biological activity

Study

name:	Location of amino acid residues important for the structure and biological function of the haemagglutinin-neuraminidase glycoprotein of Sendai virus by analysis of escape mutants.
description:	The epitope specific mAbs inhibited hemagglutination and neuraminidase from Sendai virus (strain Enders), but less or no reactivity was seen with proteins from escape mutant viruses. The mAbs were of the isotypes IgG2a (50) and IgG2b (63).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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