Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein.

Dataset

identifier:	1492169
description:	epitope description:N27, Q31, T32, K33, D35, S58, A59, D60, A61, D62, K125, K127 antigen name:Protein L1 host organism:Mus musculus antibody name:7D11
aggregation:	instance of dataset
availability:	available
primaryPublications:	17688903

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012854
landingPage:	http://www.iedb.org/assay/1492169

Publication

type:	Literature
publicationVenue:	Virology
dates:	2007

Dimension

study type:	b cell assays
subject species:	Vaccinia virus WR

Person

fullName:	Hua-Poo Su Joseph W Golden Apostolos G Gittis Jay W Hooper David N Garboczi

Data Type

method:	x-ray crystallography

Study

name:	Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein.
description:	The epitope of 7D11 Fab on the poxvirus L1 protein was determined from the crystal structure of the complex. Four copies of the Fab/L1 complex were present in the crystal asymmetric unit.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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