The latex allergen hev B 5 is an antigen with repetitive murine B-cell epitopes. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

The latex allergen hev B 5 is an antigen with repetitive murine B-cell epitopes.

Dataset

identifier:	1492131
description:	epitope description:APETEK antigen name:Hev b 5 host organism:Mus musculus BALB/c antibody name:3G3, 6A10, 6F6
aggregation:	instance of dataset
availability:	available
primaryPublications:	15241001

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012857
landingPage:	http://www.iedb.org/assay/1492131

Publication

type:	Literature
publicationVenue:	Int Arch Allergy Immunol
dates:	2004

Dimension

study type:	b cell assays
subject species:	Hevea brasiliensis

Person

fullName:	Donald H Beezhold Vicky L Hickey Michael F Sutherland Robyn E O'Hehir

Data Type

method:	western blot

Study

name:	The latex allergen hev B 5 is an antigen with repetitive murine B-cell epitopes.
description:	The epitope was deduced by a study of overlapping peptides. MAbs 6A10 and 3G3 were IgG1, and 6F6 was IgG2b. Using methionine substitution, the critical amino acid for the epitope-specific mAbs was determined to be Lys 5. Other epitopes that the mAbs recognized were PAEGEK and PAEEEK (the dominant epitope), also in Hev b 5.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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