Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Location of the major antigenic sites involved in rotavirus serotype-specific neutralization. |
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1011083 |
| landingPage: |
http://www.iedb.org/assay/1492233 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
1986
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| study type: | b cell assays |
| subject species: | Simian rotavirus A/SA11-both |
| fullName: |
M L Dyall-Smith
I Lazdins
G W Tregear
I H Holmes
|
| method: |
biological activity
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| name: |
Location of the major antigenic sites involved in rotavirus serotype-specific neutralization.
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| description: |
The epitope source is from the reference cited: Both et al. (1983) Proc Natl Acad Sci USA 80: 3091-3095 [PMID: 6304692].
The critical epitopic residue recognized by mAb RV-3:2 was determined by sequence analysis of neutralization-resistant virus mutants selected with mAbs. A virus variant with substitution T147A was not neutralized by the mAb.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |