Characterization of a broadly reactive monoclonal antibody against norovirus genogroups I and II: recognition of a novel conformational epitope.

Title:

Characterization of a broadly reactive monoclonal antibody against norovirus genogroups I and II: recognition of a novel conformational epitope.

identifier:	1489653
description:	epitope description:F426, P427, L527, A528, P529, G531 antigen name:Capsid protein VP1 host organism:Mus musculus antibody name:14-1
aggregation:	instance of dataset
availability:	available
primaryPublications:	17855545

study type:	b cell assays
subject species:	Norovirus GII

fullName:	Tomoyuki Shiota Michio Okame Sayaka Takanashi Pattara Khamrin Makiko Takagi Kenji Satou Yuichi Masuoka Fumihiro Yagyu Yuko Shimizu Hideki Kohno Masashi Mizuguchi Shoko Okitsu Hiroshi Ushijima

method:	ELISA

name:	Characterization of a broadly reactive monoclonal antibody against norovirus genogroups I and II: recognition of a novel conformational epitope.
description:	Epitope sequence was of Norovirus genogroup II genotype 4. The epitope was deduced by fragment, sequence, structural, and mutational analyses. Epitope-specific mAb recognized 15 recombinant virus-like particles (GI/1, 4, 8, 11, and GII/1-7 and 12-15) and showed weak affinity to GI/3 by Western blots and ELISA.

name:	iedb
homePage:	http://www.iedb.org

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