Structural basis for epitope sharing between group 1 allergens of cedar pollen. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Structural basis for epitope sharing between group 1 allergens of cedar pollen.

Dataset

identifier:	1489807
description:	epitope description:KSMKVTVAFNQFG antigen name:Jun a 1 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	15975657

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1005382
landingPage:	http://www.iedb.org/assay/1489807

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	2006

Dimension

study type:	b cell assays
subject species:	Juniperus ashei

Person

fullName:	Terumi Midoro-Horiuti Catherine H Schein Venkatarajan Mathura Werner Braun Edmund W Czerwinski Akihisa Togawa Yasuto Kondo Tetsuo Oka Masanao Watanabe Randall M Goldblum

Data Type

method:	western blot

Study

name:	Structural basis for epitope sharing between group 1 allergens of cedar pollen.
description:	The epitope sequence recognized by pooled serum IgE from mountain cedar allergic patients was determined through study of overlapping peptides spanning the sequence of Jun a 1. Fine mapping analysis with 8-mer peptides offset by two residues concluded that peptides 222-229 (FGPNAGQR) and 230-237 (MPRARYGL) represent two epitopes from this region.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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