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Title: Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design.
identifier: 1491784
description:
epitope description:MLSHLYVSSKDKENISKENDDVLDEKEEEAEETEEEELEEKN
antigen name:Merozoite surface protein 3
host organism:Homo sapiens
antibody name:Affinity purified sera
aggregation:
instance of dataset
availability:
available
primaryPublications: 15295710
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1012899
landingPage: http://www.iedb.org/assay/1491784
type:
Literature
publicationVenue:
J Infect Dis
dates:
2004
study type: b cell assays
subject species: Plasmodium falciparum 3D7
fullName:
Subhash Singh
Soe Soe
Juan-Pedro Mejia
Christian Roussilhon
Michael Theisen
Giampietro Corradin
Pierre Druilhe
method:
in vivo assay
name:
Identification of a conserved region of Plasmodium falciparum MSP3 targeted by biologically active antibodies to improve vaccine design.
description:
Hyperimmune sera from individuals from the Ivory Coast was affinity purified using the epitope, and these antibodies passively transferred into recipient mice decreased parasitemia by >95%.

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