Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2.

Title:

Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2.

identifier:	1493974
description:	epitope description:DMFQIGKYG host organism:Homo sapiens antibody name:anti-Der p 1
aggregation:	instance of dataset
availability:	available
primaryPublications:	17964653

study type:	b cell assays
subject species:

fullName:	Krisztina Szalai Jan Fuhrmann Tea Pavkov Michael Scheidl Julia Wallmann Kira H Brä mswig Susanne Vrtala Otto Scheiner Walter Keller Jean-Marie Saint-Remy Dirk Neumann Isabella Pali-Schö ll Erika Jensen-Jarolim

method:	phage display

name:	Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2.
description:	The mimotope was matched to the following residues in the 3D structure of the mature Der p 1 molecule: D162, M211, F150, D146, L147, R151, H152, Y153, G155. The phage-displayed epitope was selected after 3 rounds of biopanning with a Der p 1-specific human mAb.

name:	iedb
homePage:	http://www.iedb.org

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