Analysis of sequential immunoglobulin E-binding epitope of Japanese cedar pollen allergen (Cry j 2) in humans, monkeys and mice.

Title:

Analysis of sequential immunoglobulin E-binding epitope of Japanese cedar pollen allergen (Cry j 2) in humans, monkeys and mice.

identifier:	1492482
description:	epitope description:KWVNGREI antigen name:Cry j 2 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	12580914

study type:	b cell assays
subject species:	Cryptomeria japonica

fullName:	Y J Kawaguchi N Serizawa K Hirahara A Shiraishi H Nigi Y Taniguchi M S Inouye T Takemori M Sakaguchi

method:	antigen inhibition

name:	Analysis of sequential immunoglobulin E-binding epitope of Japanese cedar pollen allergen (Cry j 2) in humans, monkeys and mice.
description:	The epitope sequence was deduced. The minimal epitope recognized by serum IgE from CJ allergic patients that reacted with peptide 121-140 (GQCKWVNGREICNDRDRPTA) was deduced to be residues124-131 based on the ability of peptide 121-140 with N- or C-terminal truncations to inhibit the binding of IgE to peptide 121-140.

name:	iedb
homePage:	http://www.iedb.org

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