Antigenic importance of the carboxy-terminal beta-strand of the porcine reproductive and respiratory syndrome virus nucleocapsid protein.

Title:

Antigenic importance of the carboxy-terminal beta-strand of the porcine reproductive and respiratory syndrome virus nucleocapsid protein.

identifier:	1493146
description:	epitope description:VRLIRVTASPSA antigen name:Nucleoprotein host organism:Mus musculus BALB/c antibody name:SDOW17, VO17, EP147
aggregation:	instance of dataset
availability:	available
primaryPublications:	11329465

study type:	b cell assays
subject species:	Porcine reproductive and respiratory syndrome virus

fullName:	S Wootton G Koljesar L Yang K J Yoon D Yoo

method:	immunoprecipitation

name:	Antigenic importance of the carboxy-terminal beta-strand of the porcine reproductive and respiratory syndrome virus nucleocapsid protein.
description:	Epitope-specific mAbs recognized N protein of PRRSV strain PA8. L114P mutation abolished antibody binding, while V112P, R113P, R113D, I115P, and R116P reduced mAb binding significantly. Substitution of residues at position 118 (T118S) and 121 (P121A) had little effect on mAb binding.

name:	iedb
homePage:	http://www.iedb.org

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