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identifier: 1493310
description:
epitope description:VTGATVS
antigen name:UniProt:H6MQD5
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 8698467
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006627
landingPage: http://www.iedb.org/assay/1493310
type:
Literature
publicationVenue:
Infect Immun
dates:
1996
study type: b cell assays
subject species: Treponema pallidum subsp. pallidum str. Nichols
fullName:
R E Baughn
M Demecs
L H Taber
D M Musher
method:
ELISA
name:
Epitope mapping of B-cell determinants on the 15-kilodalton lipoprotein of Treponema pallidum (Tpp15) with synthetic peptides.
description:
After an initial assessment of reactivity with overlapping 8-mers, further definition of the epitope was attempted with shorter peptides, and this 7-mer was the optimal peptide. Alanine replacement of each residue showed that residues T2, T5, V6 and S7 were essential for antibody binding.

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