Protection against measles virus encephalitis by monoclonal antibodies binding to a cystine loop domain of the H protein mimicked by peptides which are not recognized by maternal antibodies.

Title:

Protection against measles virus encephalitis by monoclonal antibodies binding to a cystine loop domain of the H protein mimicked by peptides which are not recognized by maternal antibodies.

Dataset

identifier:	1493373
description:	epitope description:CFQQACKGKIQALCENPEWAPLKDNRIPS antigen name:Hemagglutinin glycoprotein host organism:Homo sapiens antibody name:Human sera
aggregation:	instance of dataset
availability:	available
primaryPublications:	8887481

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006504
landingPage:	http://www.iedb.org/assay/1493373

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	1996

Dimension

study type:	b cell assays
subject species:	Measles morbillivirus

Person

fullName:	D Ziegler P Fournier G A Berbers H Steuer K H Wiesmü ller B Fleckenstein F Schneider G Jung C C King C P Muller

Data Type

method:	ELISA

Study

name:	Protection against measles virus encephalitis by monoclonal antibodies binding to a cystine loop domain of the H protein mimicked by peptides which are not recognized by maternal antibodies.
description:	Human sera were tested for reactivity against the H381-409 peptide, plus several analogs of this peptide. Three sera reacted strongly with the same nine of the eleven 30-mers, 10 gave a weak reaction and 7 sera did not react with any peptide.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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