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Title: The carboxyl terminal amino acid residues of Pseudomonas aeruginosa exotoxin A involved in cell toxicity and pathogenesis, characterized by a neutralizing human monoclonal antibody.
identifier: 1497322
description:
epitope description:EQAISALPDYASQPGKPPREDLK
antigen name:Exotoxin A
host organism:Homo sapiens
antibody name:HI-1A4
aggregation:
instance of dataset
availability:
available
primaryPublications: 1719985
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006426
landingPage: http://www.iedb.org/assay/1497322
type:
Literature
publicationVenue:
Biochem Biophys Res Commun
dates:
1991
study type: b cell assays
subject species: Pseudomonas aeruginosa
fullName:
H Ohtsuka
A Higuchi
N Nomura
K Horigome
T Kohzuki
Y Nakamori
H Noguchi
method:
western blot
name:
The carboxyl terminal amino acid residues of Pseudomonas aeruginosa exotoxin A involved in cell toxicity and pathogenesis, characterized by a neutralizing human monoclonal antibody.
description:
Epitope sequence can be found in cited reference: Chow et al (1989) J Biol Chem 264:18818-18823 [PMID: 2553721].
The epitope was deduced from binding spectrum of the human mAb to fragments and deletion derivatives of Ex-A. Epitope-specific human mAb recognized Ex-A.

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