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Title: Fine specificity of the murine immune response to SV40 large tumour antigen utilizing synthetic peptides that define selected epitopes.
identifier: 1494324
description:
epitope description:CRGFTSFKKPPTPPPEPET
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 7516272
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1009121
landingPage: http://www.iedb.org/assay/1494324
type:
Literature
publicationVenue:
Clin Exp Immunol
dates:
1994
study type: b cell assays
subject species:
fullName:
R K Bright
M H Shearer
R C Kennedy
method:
in vivo assay
name:
Fine specificity of the murine immune response to SV40 large tumour antigen utilizing synthetic peptides that define selected epitopes.
description:
The Cys residue at position 6 of the natural sequence was replaced by Ser to prevent intrachain disulfide bond formation.
BALB/c mice immunized with epitope-KLH conjugate demonstrated a 50% survival rate for longer than 60 days after a tumor challenge with a lethal dose of SV40-transformed cells.

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