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Title: Fine specificity of the murine immune response to SV40 large tumour antigen utilizing synthetic peptides that define selected epitopes.
identifier: 1494310
description:
epitope description:CRGFTSFKKPPTPPPEPET
host organism:Mus musculus BALB/c
antibody name:Pab 405, Pab 101
aggregation:
instance of dataset
availability:
available
primaryPublications: 7516272
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1009121
landingPage: http://www.iedb.org/assay/1494310
type:
Literature
publicationVenue:
Clin Exp Immunol
dates:
1994
study type: b cell assays
subject species:
fullName:
R K Bright
M H Shearer
R C Kennedy
method:
ELISA
name:
Fine specificity of the murine immune response to SV40 large tumour antigen utilizing synthetic peptides that define selected epitopes.
description:
The Cys residue at position 6 of the natural sequence was replaced by Ser to prevent intrachain disulfide bond formation.
MAb Pab 405 reacted strongly with the epitope and mAb Pab 101 reacted more weakly. The epitope inhibited the binding of mAbs Pab 405 and Pab 101 to SV40 T-ag by 21% and 25%, respectively.

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