Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1006318 |
| landingPage: |
http://www.iedb.org/assay/1494374 |
| type: |
Literature
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| publicationVenue: |
Mol Immunol
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| dates: |
1994
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| study type: | b cell assays |
| subject species: |
| fullName: |
R K Bright
M H Shearer
R C Kennedy
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| method: |
in vivo assay
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| name: |
SV40 large tumor antigen associated synthetic peptides define native antigenic determinants and induce protective tumor immunity in mice.
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| description: |
The CG added at the N-terminus for coupling. The penultimate Gln residue was replaced by Asn.
Mice were challenged with an i.p.inoculation of 5 LD50 (equal to 2.5 x 10^5 SV40-transformed cells) of a BALB/c SV40-transformed kidney fibroblast cell line (mKSA) 14 days after a final booster injection. BALB/c mice immunized with epitope-KLH conjugate did not survive a tumor challenge past 30 days (survival time = 7-22 days).
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
