Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.

Title:

Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.

Dataset

identifier:	1494391
description:	epitope description:VDHTNFKYNYSVIEGGPIGDTLEKISNEIK antigen name:Bet v 1 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	17911617

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012672
landingPage:	http://www.iedb.org/assay/1494391

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2007

Dimension

study type:	b cell assays
subject species:	Betula pendula

Person

fullName:	Ines Pree Jü rgen Reisinger Margit Focke Susanne Vrtala Gabrielle Pauli Marianne van Hage Oliver Cromwell Elisabeth Gadermaier Cornelia Egger Norbert Reider Friedrich Horak Rudolf Valenta Verena Niederberger

Data Type

method:	in vivo assay

Study

name:	Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.
description:	The epitope sequence appears in Focke et al (2004) [PMID: 15479266]. Immunotherapy with Bet v 1 fragments did not lead to decreases in reactivity of IgE, IgG1, IgG4, IgA or IgM to the epitope, but led to some increase in IgG1.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.