Structural characterization of immunodominant regions of streptokinase recognized by murine monoclonal antibodies.

Title:

Structural characterization of immunodominant regions of streptokinase recognized by murine monoclonal antibodies.

identifier:	1495594
description:	epitope description:MKNYLSFGMFALL antigen name:Streptokinase host organism:Mus musculus A/J antibody name:A2.5
aggregation:	instance of dataset
availability:	available
primaryPublications:	8823613

study type:	b cell assays
subject species:	Streptococcus dysgalactiae subsp. equisimilis

fullName:	B Parhami-Seren G L Reed

method:	western blot

name:	Structural characterization of immunodominant regions of streptokinase recognized by murine monoclonal antibodies.
description:	The epitope sequence according to Malke, H., B. Roe, and J. J. Ferretti. 1985. Nucleotide sequence of the streptokinase gene from Streptococcus equisimilis H46A. Gene 34:357&ndash 362 [PMID: 2989113]. The epitope sequence was deduced through study of overlapping peptides. The mAb A2.5 did not inhibit the formation of a functional SKPAC , measured by inhibition of SK binding to Glu-plasminogen. Binding by the epitope-specific mAb was inhibited by another epitope-specific mAb (9D10).

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.