Characterisation of a linear binding site for a monoclonal antibody to hepatitis B core antigen. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Characterisation of a linear binding site for a monoclonal antibody to hepatitis B core antigen.

Dataset

identifier:	1495856
description:	epitope description:EDPASR antigen name:Capsid protein host organism:Mus musculus antibody name:35/312
aggregation:	instance of dataset
availability:	available
primaryPublications:	1713264

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1012821
landingPage:	http://www.iedb.org/assay/1495856

Publication

type:	Literature
publicationVenue:	J Med Virol
dates:	1991

Dimension

study type:	b cell assays
subject species:	Hepatitis B virus subtype ayw

Person

fullName:	M Sä llberg U Rudé n L O Magnius H P Harthus M Noah B Wahren

Data Type

method:	ELISA

Study

name:	Characterisation of a linear binding site for a monoclonal antibody to hepatitis B core antigen.
description:	The epitope was mapped using overlapping decapeptides. Residues at positions 2 and 3 of the epitope were found to be critical for monoclonal antibody reactivity. The C-terminal D residue that was included in the peptide during screening was found not to be essential for the formation of the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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