Peptide vaccine against canine parvovirus: identification of two neutralization subsites in the N terminus of VP2 and optimization of the amino acid sequence.

Title:

Peptide vaccine against canine parvovirus: identification of two neutralization subsites in the N terminus of VP2 and optimization of the amino acid sequence.

Dataset

identifier:	1498236
description:	epitope description:GGQPAVRNER antigen name:Capsid protein VP1 host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	7474152

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008187
landingPage:	http://www.iedb.org/assay/1498236

Publication

type:	Literature
publicationVenue:	J Virol
dates:	1995

Dimension

study type:	b cell assays
subject species:	Canine parvovirus

Person

fullName:	J I Casal J P Langeveld E Corté s W W Schaaper E van Dijk C Vela S Kamstrup R H Meloen

Data Type

method:	biological activity

Study

name:	Peptide vaccine against canine parvovirus: identification of two neutralization subsites in the N terminus of VP2 and optimization of the amino acid sequence.
description:	The epitope specific antiserum was positive in a virus neutralization test, and recognized the virus in a direct binding ELISA. The antibody titers and neutralization values obtained were 1 order of magnitude higher for peptides linked via the N terminus to keyhole limpet hemocyanin than for those linked through the C terminus.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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