Molecular characterization of a subgroup specificity associated with the rotavirus inner capsid protein VP2.

Title:

Molecular characterization of a subgroup specificity associated with the rotavirus inner capsid protein VP2.

identifier:	1501245
description:	epitope description:M452, R454, R458, P462, Q463, Q467, Q474, A479, R491, L499, N506, V512, M521,Q522, Q527, P529 antigen name:Inner capsid protein VP2 host organism:Mus musculus antibody name:6E8
aggregation:	instance of dataset
availability:	available
primaryPublications:	18216104

study type:	b cell assays
subject species:	Human rotavirus strain WA

fullName:	Sarah M McDonald John T Patton

method:	immuno staining

name:	Molecular characterization of a subgroup specificity associated with the rotavirus inner capsid protein VP2.
description:	These residues are conserved among most human rotavirus A, and are thus potentially involved in the recognition by a mAb, as they differ between recognized and not recognized types of rotavirus. Epitope-specific MAb stains MA104 (fetal monkey kidney) cells infected with simian rotavirus A strain SA-11, in a specific manner and colocalized with VP1. Specific detection of VP2 from virus is also seen in immunoprecipitation studies.

name:	iedb
homePage:	http://www.iedb.org

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