Protection of swine from foot-and-mouth disease with one dose of an all-D retro peptide. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Protection of swine from foot-and-mouth disease with one dose of an all-D retro peptide.

Dataset

identifier:	1500183
description:	epitope description:GSGVRGDFGSLAPRVARQL + D-aa(G1,S2,G3,V4,R5,G6,D7,F8,G9,S10,L11,A12,P13,R14,V15,A16,R17,Q18,L19) antigen name:Genome polyprotein host organism:Sus scrofa
aggregation:	instance of dataset
availability:	available
primaryPublications:	10438060

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006611
landingPage:	http://www.iedb.org/assay/1500183

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	1999

Dimension

study type:	b cell assays
subject species:	Foot-and-mouth disease virus (strain A12)

Person

fullName:	F Nargi E Kramer J Mezencio J Zamparo C Whetstone M H Van Regenmortel J P Briand S Muller F Brown

Data Type

method:	ELISA

Study

name:	Protection of swine from foot-and-mouth disease with one dose of an all-D retro peptide.
description:	The peptide is an all-D retro peptide corresponding to the GH loop encompassing residue 141-159 of capsid protein VP1 of foot-and-mouth disease virus serotype A, subtype 12, referenced in Briand J.P. et al 1997. PNAS 94:12545 [PMID:9356486]. The results obtained by ELISA were confirmed by Radioimmunoprecipitation of virus-induced proteins produced in BHK cells. Two animals did not develop antibodies against 3ABC, indicating that virus replication had not taken place. Results from two animals 7were only very weakly positive and the findings were not confirmed by RIP.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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