Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1006183 |
| landingPage: |
http://www.iedb.org/assay/1501619 |
| type: |
Literature
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| publicationVenue: |
Infect Immun
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| dates: |
2003
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| study type: | b cell assays |
| subject species: | Treponema pallidum subsp. pallidum (strain Chicago) |
| fullName: |
Cecilia A Morgan
Sheila A Lukehart
Wesley C Van Voorhis
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| method: |
ELISA
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| name: |
Protection against syphilis correlates with specificity of antibodies to the variable regions of Treponema pallidum repeat protein K.
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| description: |
This peptide is located at one of the seven variable regions of the protein, which differ between strain Nichols and Chicago of T. pallidum subsp. pallidum.
The sera were obtained 180 days after the induction of infection, when the animals are immune to homologous challenge. Previous immunization of animals with a recombinant N-terminal fragment of TprK (strain Nichols) did not significantly affect the recognition of this peptide.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
