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identifier: 1502312
description:
epitope description:RPYCWHYPP
antigen name:Genome polyprotein
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 18256830
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013221
landingPage: http://www.iedb.org/assay/1502312
type:
Literature
publicationVenue:
Cancer Immunol Immunother
dates:
2008
study type: b cell assays
subject species: Hepatitis C virus (isolate 1)
fullName:
Darja Kanduc
Luciana Tessitore
Guglielmo Lucchese
Anthony Kusalik
Emanuel Farber
Francesco M Marincola
method:
ELISA
name:
Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response.
description:
This peptide corresponds to the E2/NS1 region of the polyprotein. This peptide has a null similarity level in comparison with the human proteome
no occurrences of a match for any the possible 5-mers contained in this peptide is found in the human proteome. The peptide is 100% conserved in subtype 1a (isolate H), subtype 1b (strain BK), subtype 2b (strains HC-J8 and JPUT971017) and subtype 2a (strains JFH-1 and HC-J6), while it has a single substitution in subtype 1b (strains Taiwan, Con1, Japanese and HC-JT).
Partially purified antibody preparations from each sera were analyzed.

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