| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1013221 |
| landingPage: |
http://www.iedb.org/assay/1502312 |
| type: |
Literature
|
| publicationVenue: |
Cancer Immunol Immunother
|
| dates: |
2008
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus (isolate 1) |
| fullName: |
Darja Kanduc
Luciana Tessitore
Guglielmo Lucchese
Anthony Kusalik
Emanuel Farber
Francesco M Marincola
|
| method: |
ELISA
|
| name: |
Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response.
|
| description: |
This peptide corresponds to the E2/NS1 region of the polyprotein. This peptide has a null similarity level in comparison with the human proteome
no occurrences of a match for any the possible 5-mers contained in this peptide is found in the human proteome. The peptide is 100% conserved in subtype 1a (isolate H), subtype 1b (strain BK), subtype 2b (strains HC-J8 and JPUT971017) and subtype 2a (strains JFH-1 and HC-J6), while it has a single substitution in subtype 1b (strains Taiwan, Con1, Japanese and HC-JT).
Partially purified antibody preparations from each sera were analyzed.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |