Japanese encephalitis protein vaccine candidates expressing neutralizing epitope and M.T hsp70 induce virus-specific memory B cells and long-lasting antibodies in swine.

Title:

Japanese encephalitis protein vaccine candidates expressing neutralizing epitope and M.T hsp70 induce virus-specific memory B cells and long-lasting antibodies in swine.

Dataset

identifier:	1502517
description:	epitope description:EMEPPFGDSYIVVGRGDKQINHHWHKA antigen name:Genome polyprotein host organism:Sus scrofa Yorkshire
aggregation:	instance of dataset
availability:	available
primaryPublications:	18761388

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013145
landingPage:	http://www.iedb.org/assay/1502517

Publication

type:	Literature
publicationVenue:	Vaccine
dates:	2008

Dimension

study type:	b cell assays
subject species:	Japanese encephalitis virus strain SA-14

Person

fullName:	Ge Fei-fei Wang Jian Xu Feng Sheng Li-ping Sun Quan-yun Zhou Jin-ping Chen Pu-yan Liu Pei-hong

Data Type

method:	ELISA

Study

name:	Japanese encephalitis protein vaccine candidates expressing neutralizing epitope and M.T hsp70 induce virus-specific memory B cells and long-lasting antibodies in swine.
description:	The sequence of the peptide is reported in Ge et al, Arch Virol 2007 152:12 [PMID 16862385]. This conserved sequence is also present in the strain JaOArS982. Castrated males and females of the Yorkshire breed were used. Immunizations were also performed without conjugation to HSP70, but with the following adjuvants: S206 or mineral oil and Tween-80.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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