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identifier: 1503052
description:
epitope description:VDHVGLGTAFENSIY
antigen name:Capsid protein
host organism:Sus scrofa
aggregation:
instance of dataset
availability:
available
primaryPublications: 11504425
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006379
landingPage: http://www.iedb.org/assay/1503052
type:
Literature
publicationVenue:
Arch Virol
dates:
2001
study type: b cell assays
subject species: Porcine circovirus 2
fullName:
C
D Mahe
P Blanchard
M Le Dimna
F Madec
A Jestin
E Albina
method:
ELISA
name:
Identification of an immunorelevant ORF2 epitope from porcine circovirus type 2 as a serological marker for experimental and natural infection.
description:
This epitope sequence is from the reference cited: Mahe et al. (2000) J Gen Virol 81: 1815-1824 [PMID: 10859388].
Sera from PCV2-immunized specific pathogen-free piglets or conventional farm piglets reacted with the epitope in a pepscan analysis of overlapping peptides. Reactivity with the epitope by ELISA increased 1.6-fold in the SPF piglets and 1.8-fold in the farm piglets 6 weeks post-inoculation compared to the pre-immune serum. The ratio of reactivity with the epitope versus the analogous peptide from PCV1 was 1.1-1.3, indicating the epitope is not PCV2 discriminant.

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