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Title: The effect of amino acid spacers on the antigenicity of dimeric peptide--inducing cross-reacting antibodies to a cell surface protein antigen of Streptococcus mutans.
identifier: 1503114
description:
epitope description:TYEAALKQYEADL
antigen name:UniProt:I6TX52
host organism:Mus musculus B10.D2
aggregation:
instance of dataset
availability:
available
primaryPublications: 11169138
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1009726
landingPage: http://www.iedb.org/assay/1503114
type:
Literature
publicationVenue:
Oral Microbiol Immunol
dates:
2001
study type: b cell assays
subject species: Streptococcus mutans
fullName:
Y Oishi
A Onozuka
H Kato
N Shimura
S Imai
T Nisizawa
method:
ELISA
name:
The effect of amino acid spacers on the antigenicity of dimeric peptide--inducing cross-reacting antibodies to a cell surface protein antigen of Streptococcus mutans.
description:
Sera from mice immunized with the epitope or tandem constructs of the epitope reacted with recombinant PAc protein. The best response was achieved with the tandem epitope with one or two lysine residues as a spacer between the unit epitope, administered with or without adjuvant.

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