Molecular basis for the cross-reactivity of antibodies elicited by a natural anatoxin with alpha- and beta-toxins from the venom of Tityus serrulatus scorpion.

Title:

Molecular basis for the cross-reactivity of antibodies elicited by a natural anatoxin with alpha- and beta-toxins from the venom of Tityus serrulatus scorpion.

Dataset

identifier:	1503586
description:	epitope description:GLPDSVKIWTSETNK antigen name:Toxin Ts4 host organism:Equus caballus antibody name:anti-TsNTxP
aggregation:	instance of dataset
availability:	available
primaryPublications:	11922945

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008052
landingPage:	http://www.iedb.org/assay/1503586

Publication

type:	Literature
publicationVenue:	Mol Immunol
dates:	2002

Dimension

study type:	b cell assays
subject species:	Tityus serrulatus

Person

fullName:	Carlos Chavez-Olortegui Franck Molina Claude Granier

Data Type

method:	western blot

Study

name:	Molecular basis for the cross-reactivity of antibodies elicited by a natural anatoxin with alpha- and beta-toxins from the venom of Tityus serrulatus scorpion.
description:	The epitope-specific antiserum reacted strongly with the peptide. By testing alanine analogs of the peptides, Asp 50, Trp 55, Glu 58 and Lys 61 were identified as key-residues.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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