MHC-peptide-specific antibodies reveal inefficient presentation of an HLA-A*0201-restricted, Melan-A-derived peptide after active intracellular processing.

Title:

MHC-peptide-specific antibodies reveal inefficient presentation of an HLA-A*0201-restricted, Melan-A-derived peptide after active intracellular processing.

Dataset

identifier:	1503888
description:	epitope description:ELAGIGILTV host organism:Homo sapiens antibody name:2M3F11, 3N4E9, 2N4B4, 3N4B5, E6, H4
aggregation:	instance of dataset
availability:	available
primaryPublications:	17559180

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1007952
landingPage:	http://www.iedb.org/assay/1503888

Publication

type:	Literature
publicationVenue:	Eur J Immunol
dates:	2007

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Gerhard Held Andreas Wadle Nina Dauth Guillaume Stewart-Jones Christine Sturm Markus Thiel Carsten Zwick Detlef Dieckmann Gerold Schuler Hennie R Hoogenboom Fré dé ric Lé vy Vincenzo Cerundolo Michael Pfreundschuh Christoph Renner

Data Type

method:	flow cytometry

Study

name:	MHC-peptide-specific antibodies reveal inefficient presentation of an HLA-A*0201-restricted, Melan-A-derived peptide after active intracellular processing.
description:	Staining intensity was dependent on the peptide concentration used for pulsing. In a further experiment, ELA / HLA-A*0201 peptide complexes increased largely in E6 antibody-detected peptide numbers.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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