Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray-based immunoassay.

Title:

Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray-based immunoassay.

identifier:	1505514
description:	epitope description:KNTMEHVSSSEESIISQETY antigen name:Bos d 10 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	18774394

study type:	b cell assays
subject species:	Bos taurus

fullName:	Inmaculada Cerecedo Javier Zamora Wayne G Shreffler Jing Lin Ludmilla Bardina Ma Carmen Dieguez Julie Wang Alfonso Muriel Belé n de la Hoz Hugh A Sampson

method:	microarray

name:	Mapping of the IgE and IgG4 sequential epitopes of milk allergens with a peptide microarray-based immunoassay.
description:	Reactivity is expressed as the IgE/IgG4 ratio. Absolute and relative frequencies of patients' antibodies recognizing each epitope were determined. Peptides that were bound by antibodies from greater than 75% of patients with milk allergy were considered epitopes. For the reactive and tolerant groups, 12/16 patients and 2/15 patients responded positively to the assay, respectively. This difference in reactivity is significant.

name:	iedb
homePage:	http://www.iedb.org

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