Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells.

Title:

Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells.

identifier:	1511443
description:	epitope description:LAPISGTVQSAHLIIRFD antigen name:Fiber protein host organism:Mus musculus BALB/c antibody name:1D6.3
aggregation:	instance of dataset
availability:	available
primaryPublications:	9171344

study type:	b cell assays
subject species:	Human adenovirus 5

fullName:	S S Hong L Karayan J Tournier D T Curiel P A Boulanger

method:	phage display

name:	Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells.
description:	The epitope was deduced. The epitopic region recognized by mAb 1D6.3, which recognizes a conformational epitope, was mapped based on sequence homology of phage-displayed random hexapeptides to the sequence of Ad5 fiber knob. The deduced epitope maps to the knob domain facing the cell receptor.

name:	iedb
homePage:	http://www.iedb.org

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