Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells.

Title:

Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells.

identifier:	1511467
description:	epitope description:LIPFNS host organism:Mus musculus BALB/c antibody name:1D6.3
aggregation:	instance of dataset
availability:	available
primaryPublications:	9171344

study type:	b cell assays
subject species:

fullName:	S S Hong L Karayan J Tournier D T Curiel P A Boulanger

method:	phage display

name:	Adenovirus type 5 fiber knob binds to MHC class I alpha2 domain at the surface of human epithelial and B lymphoblastoid cells.
description:	The phage-displayed epitope was selected by mAb 1D6.3, which recognizes a conformational epitope, from a phage library of random hexapeptides. The epitope of mAb 1D6.3 was deduced to be within residues 445-462 (LAPISGTVQSAHLIIRFD) based on homology of the phage clones to the sequence of Ad5 fiber knob.

name:	iedb
homePage:	http://www.iedb.org

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