Epsilon-binding regions of the gamma subunit of Escherichia coli ATP synthase. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Epsilon-binding regions of the gamma subunit of Escherichia coli ATP synthase.

Dataset

identifier:	1510670
description:	epitope description:RKVIGHLAHGNLEYKHPYLEDR antigen name:ATP synthase gamma chain host organism:Rattus norvegicus antibody name:gamma-1
aggregation:	instance of dataset
availability:	available
primaryPublications:	9131043

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1009735
landingPage:	http://www.iedb.org/assay/1510670

Publication

type:	Literature
publicationVenue:	Biochim Biophys Acta
dates:	1997

Dimension

study type:	b cell assays
subject species:	Escherichia coli

Person

fullName:	S D Dunn

Data Type

method:	western blot

Study

name:	Epsilon-binding regions of the gamma subunit of Escherichia coli ATP synthase.
description:	The epitope sequence is from the reference cited previously by the authors: Walker et al. (1984) Biochim Biophys Acta 768: 164-200 [PMID: 6206892]. The epitope was deduced. The epitope-specific mAb gamma-1 bound to ATPase synthase gamma subunit and competed the binding of ε to the gamma subunit. In separate experiments, mAb gamma-1 bound to ε-depleted F1-ATPase but only to trace amounts of normal F1-ATPase. The authors conclude that the epitope for mAb gamma-1 is occluded by the binding of ε to the enzyme.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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