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Title: Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection.
identifier: 1511769
description:
epitope description:AATTVNGGTVHFK
antigen name:Type-1 fimbrial protein, A chain
host organism:Oryctolagus cuniculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 9276729
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1006497
landingPage: http://www.iedb.org/assay/1511769
type:
Literature
publicationVenue:
J Clin Invest
dates:
1997
study type: b cell assays
subject species: Escherichia coli
fullName:
K Thankavel
B Madison
R Malaviya
A H Shah
P M Arumugam
S N Abraham
method:
in vivo assay
name:
Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infection.
description:
The author confirmed the sequence of the peptide used, and assigned its source to the sequence published in Klemm P., Eur. J. Biochem. (1984) 143: 395-399 [PMID:6147250] which is the origin of the accession provided.
The levels of bacteria in the bladder of mice five days after intravesicular challenge with E.coli CI5 were analyzed. Mice passively immunized with epitope-specific rabbit serum 24 hours before challenge had similar levels of bacteria as controls.

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