Synthetic peptides of the E2 glycoprotein of Venezuelan equine encephalomyelitis virus. II. Antibody to the amino terminus protects animals by limiting viral replication.

Title:

Synthetic peptides of the E2 glycoprotein of Venezuelan equine encephalomyelitis virus. II. Antibody to the amino terminus protects animals by limiting viral replication.

Dataset

identifier:	1513914
description:	epitope description:STEELFNEYKLTRPYMARCIRCAVG antigen name:Structural polyprotein host organism:Mus musculus NHI Swiss
aggregation:	instance of dataset
availability:	available
primaryPublications:	1718085

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1006639
landingPage:	http://www.iedb.org/assay/1513914

Publication

type:	Literature
publicationVenue:	Virology
dates:	1991

Dimension

study type:	b cell assays
subject species:	Venezuelan equine encephalitis virus (strain Trinidad donkey)

Person

fullName:	A R Hunt W A Short A J Johnson R A Bolin J T Roehrig

Data Type

method:	in vivo assay

Study

name:	Synthetic peptides of the E2 glycoprotein of Venezuelan equine encephalomyelitis virus. II. Antibody to the amino terminus protects animals by limiting viral replication.
description:	The epitope sequence is from the cited reference Hunt, A.R. et al. Virology (1990), 179, 701-711. [ PMID: 2146802 ]. 90% of mice were protected from challenge when undiluted polyclonal antipeptide antibody was used for passive transfer, but in the groups that received diluted antibody, the number of survivors was not significant.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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