Homotypic and heterotypic neutralization determinants of bluetongue virus serotype 17. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Homotypic and heterotypic neutralization determinants of bluetongue virus serotype 17.

Dataset

identifier:	1549677
description:	epitope description:G327, E582 antigen name:Outer capsid protein VP2 host organism:Mus musculus BALB/c antibody name:034
aggregation:	instance of dataset
availability:	available
primaryPublications:	7538255

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008772
landingPage:	http://www.iedb.org/assay/1549677

Publication

type:	Literature
publicationVenue:	Virology
dates:	1995

Dimension

study type:	b cell assays
subject species:	Bluetongue virus 17

Person

fullName:	C M Pierce P V Rossitto N J MacLachlan

Data Type

method:	biological activity

Study

name:	Homotypic and heterotypic neutralization determinants of bluetongue virus serotype 17.
description:	The epitope-specific mAb(s) neutralized Bluetongue virus 17. Escape mutant viruses had G327D and E582Q mutations. Amino acids 327 and 528 synergistically affect the binding of mAb 034.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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