Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.

Title:

Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.

Dataset

identifier:	1556649
description:	epitope description:K198, E210 antigen name:Other Neisseria meningitidis protein host organism:Mus musculus CD1 antibody name:JAR 10
aggregation:	instance of dataset
availability:	available
primaryPublications:	18591239

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013412
landingPage:	http://www.iedb.org/assay/1556649

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	2008

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis serogroup B Strain 8047

Person

fullName:	Peter T Beernink Jo Anne Welsch Michal Bar-Lev Oliver Koeberling Maurizio Comanducci Dan M Granoff

Data Type

method:	ELISA

Study

name:	Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.
description:	This strain expresses a fHBP of the v.2 group. The epitope-specific mAb did not bound to other strain (MC58) expressing fHbp in the same group (v.1). It did not react with any strains expressing fHbp in the v.3 group.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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