Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.

Title:

Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.

Dataset

identifier:	1557263
description:	epitope description:S234 antigen name:Other Neisseria meningitidis protein host organism:Mus musculus CD1 antibody name:JAR 13
aggregation:	instance of dataset
availability:	available
primaryPublications:	18591239

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013412
landingPage:	http://www.iedb.org/assay/1557263

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	2008

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis serogroup B Strain 8047

Person

fullName:	Peter T Beernink Jo Anne Welsch Michal Bar-Lev Oliver Koeberling Maurizio Comanducci Dan M Granoff

Data Type

method:	ELISA

Study

name:	Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.
description:	This strain expresses a fHBP of the v.2 group. Epitope specific mAb reacted with N.meningiditis expressing fHBP in the group v.3 (strains M1239 and GB988) but did not react with any strains expressing fHbp in the v.1 group.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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