Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.

Title:

Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.

Dataset

identifier:	1557272
description:	epitope description:R206, E218 antigen name:Other Neisseria meningitidis protein host organism:Mus musculus CD1 antibody name:JAR 33
aggregation:	instance of dataset
availability:	available
primaryPublications:	18591239

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013412
landingPage:	http://www.iedb.org/assay/1557272

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	2008

Dimension

study type:	b cell assays
subject species:	Neisseria meningitidis serogroup B Strain M1239

Person

fullName:	Peter T Beernink Jo Anne Welsch Michal Bar-Lev Oliver Koeberling Maurizio Comanducci Dan M Granoff

Data Type

method:	ELISA

Study

name:	Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.
description:	This strain expresses a fHBP of the v.3 group. The epitope-specific mAb reacted with the strain expressing the immunogen fHbp v.3 but not with other strain (GB988) expressing fHbp in the same group or with strains expressing fHbp in the v.1 group.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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